Green Copper Catalysis in Enantioselective Domino Reactions
نویسندگان
چکیده
منابع مشابه
Enantioselective Stereodivergent Nucleophile‐Dependent Isothiourea‐Catalysed Domino Reactions
α,β-Unsaturated acyl ammoniums generated from the reaction of α,β-unsaturated 2,4,6-trichlorophenol (TCP) esters bearing a pendent enone with an isothiourea organocatalyst are versatile intermediates in a range of enantioselective nucleophile-dependent domino processes to form complex products of diverse topology with excellent stereoselectivity. Use of either 1,3-dicarbonyls, acyl benzothiazol...
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The enantioselective domino reaction between CO2 (1 atm), amines and linear allyl chlorides in the presence of an iridium complex, DABCO and toluene at 15 °C was realized, which gave branched allyl carbamates in acceptable to high yields with up to excellent regioselectivity (99/1) and 94% ee. This is the first example of the synthesis of chiral allyl carbamates through catalytic domino reactio...
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Reported herein is a photochemical cascade process that combines the excited-state and ground-state reactivity of chiral organocatalytic intermediates. This strategy directly converts racemic cyclopropanols and α,β-unsaturated aldehydes into stereochemically dense cyclopentanols with exquisite stereoselectivity. Mechanistic investigations have enabled elucidating the origin of the stereoconverg...
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ژورنال
عنوان ژورنال: Current Organic Chemistry
سال: 2019
ISSN: 1385-2728
DOI: 10.2174/1385272822666181207150337